GLN1 anticorps (AA 50-250)

N° du produit ABIN7875382

Cet anticorps anti-GLN1 Monoclonal Souris (Clone GLUL-6601) (ABIN7875382) détecte spécifiquement GLN1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Chien.

Aperçu rapide pour GLN1 anticorps (AA 50-250) (ABIN7875382)

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Reactivité: Humain, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GLUL-6601

Détail du produit anti-GLN1 anticorps

Épitope: AA 50-250

Fonction: Glutamine Synthetase Antibody / GLUL

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the Glutamine Synthetase antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Glutamine Synthetase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Glutamine Synthetase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GLN1

Antigène: GLN1 (Glutamine Synthetase (GLN1))

Autre désignation: Glutamine Synthetase

Sujet: Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion