Netrin 3 anticorps (AA 51-473)

N° du produit ABIN7875521

Cet anticorps Lapin Polyclonal détecte spécifiquement Netrin 3 dans WB, ELISA, IHC (p) et IF. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Netrin 3 anticorps (AA 51-473) (ABIN7875521)

Antigène: Netrin 3 (Ntn3)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Netrin 3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Netrin 3 anticorps

Épitope: AA 51-473

Fonction: NTN3 Antibody / Netrin 3

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (R51-R473) was used as the immunogen for the NTN3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the NTN3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the NTN3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Netrin 3

Antigène: Netrin 3 (Ntn3)

Autre désignation: NTN3

Sujet: Netrins are a family of highly conserved proteins responsible for axon guidance and cell movement throughout neural development. Netrins can be divided into secreted netrins (netrin 1,3,4 and 5) and membrane-tethered glycophosphatidylinositol (GPI)-linked netrins (netrin G1 and G2). Secreted netrins carry their function via interaction with several receptors that include the deleted in colorectal (DCC) family, and the uncoordinated-5 (UNC5-A through UNC5-D) family. Netrin-3 was discovered in 1997 using sequence homology searching of netrin-2. Similarly to other netrins, Netrin-3 plays an important role in the development of the nervous system. Netrin-3 structure consist of a laminin-like domain located on the N-terminal, three epidermal growth factors like repeats (EGF), and a C-terminal netrin-like domain (NTR). Mutations in NTN3, the gene encoding netrin-3 was found to be associated with the development of several carcinomas.

UniProt: O00634

Pathways: Regulation of Muscle Cell Differentiation