BCL6 anticorps (AA 528-601)
Aperçu rapide pour BCL6 anticorps (AA 528-601) (ABIN7875587)
Antigène
Voir toutes BCL6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
-
-
Épitope
- AA 528-601
-
Fonction
- BCL6 Antibody / B-Cell Lymphoma 6 Protein (azide and preservative free)
-
Purification
- Protein A/G affinity
-
Immunogène
- A recombinant partial protein sequence (within amino acids 528-601) from the human protein was used as the immunogen for the BCL6 antibody.
-
Isotype
- IgG2b
-
-
-
-
Indications d'application
- Optimal dilution of the BCL6 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot the BCL6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
-
Autre désignation
- BCL6
-
Sujet
- Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
-
UniProt
- P41182
-
Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Antigène
-