RNF216 anticorps (AA 538-813)

N° du produit ABIN7875630

L’anticorps anti-RNF216 Polyclonal Lapin est utilisé pour la détection de RNF216 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour RNF216 anticorps (AA 538-813) (ABIN7875630)

Antigène: RNF216 (Ring Finger Protein 216 (RNF216))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF216 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-RNF216 anticorps

Épitope: AA 538-813

Fonction: RNF216 Antibody / TRIAD3

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids K538-R813) was used as the immunogen for the RNF216 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RNF216 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RNF216 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RNF216

Antigène: RNF216 (Ring Finger Protein 216 (RNF216))

Autre désignation: RNF216

Sujet: E3 ubiquitin-protein ligase RNF216 is an enzyme that in humans is encoded by the RNF216 gene. This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.

UniProt: Q9NWF9