Occludin anticorps (AA 54-270)

N° du produit ABIN7875650

Cet anticorps Lapin Polyclonal détecte spécifiquement Occludin dans WB, ELISA, FACS, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Occludin anticorps (AA 54-270) (ABIN7875650)

Antigène: Occludin (OCLN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Occludin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Occludin anticorps

Épitope: AA 54-270

Fonction: OCLN Antibody / Occludin

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids H54-K270) was used as the immunogen for the OCLN antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the OCLN antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the OCLN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Occludin

Antigène: Occludin (OCLN)

Autre désignation: OCLN

Sujet: Occludin is an integral membrane protein that is located at tight junctions. It is a member of a family of proteins containing the highly conserved Marvel domain, which contains 4 transmembrane-helix regions. This gene is mapped to 5q13.2. Occludin regulates TGF-beta receptor type I localization for efficient TGF-beta-dependent dissolution of tight junctions during epithelial-mesenchymal transitions. Human Occludin is an essential hepatitis C virus (HCV) cell entry factor that is able to render murine cells infectable with HCV glycoproteins. It has been found that occludin is involved in cell migration and functions to recruit active PI3 kinase to the leading edge, resulting in RAC1 activation and formation of lamellipodia.

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C