CD166 anticorps (AA 54-509)

N° du produit ABIN7875654

L’anticorps anti-CD166 Polyclonal Lapin est utilisé pour la détection de CD166 dans des échantillons de Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC (p).

Aperçu rapide pour CD166 anticorps (AA 54-509) (ABIN7875654)

Antigène: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD166 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD166 anticorps

Épitope: AA 54-509

Fonction: Zebrafish Alcama Antibody / Neurolin

Purification: Antigen affinity chromatography

Immunogène: E. coli-derived zebrafish Alcama recombinant protein (amino acids K54-I509) was used as the immunogen for the Zebrafish Alcama antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Alcama antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Alcama antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD166

Antigène: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Autre désignation: Alcama

Sujet: Activated leukocyte cell adhesion molecule a (Alcama), also known as Neurolin, is a member of the immunoglobulin superfamily of cell adhesion molecules. In zebrafish (Danio rerio), Alcama plays a vital role in axon guidance, cell-cell adhesion, and tissue morphogenesis, particularly during the development of the nervous system, vasculature, and hematopoietic system.

Alcama is prominently expressed in developing neurons, where it mediates axon fasciculation and growth cone navigation, facilitating the formation of organized neuronal tracts. In addition to its role in neurodevelopment, zebrafish Alcama is expressed in vascular endothelial cells and hematopoietic stem and progenitor cells (HSPCs), where it contributes to vasculogenesis, vascular remodeling, and stem cell niche formation.

Due to its conserved structure and multifunctional roles, zebrafish Alcama is a valuable model for studying cell adhesion dynamics, nervous system wiring, hematopoietic development, and angiogenesis. It is also used in research related to immune cell migration, axon pathfinding disorders, and regenerative medicine.

UniProt: Q90460