PCDHGC4 anticorps (AA 57-770)
Aperçu rapide pour PCDHGC4 anticorps (AA 57-770) (ABIN7875812)
Antigène
Voir toutes PCDHGC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 57-770
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Fonction
- PCDHGC4 Antibody / Protocadherin gamma-C4
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived human recombinant protein (amino acids D57-H770) was used as the immunogen for the PCDHGC4 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the PCDHGC4 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the PCDHGC4 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))
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Autre désignation
- PCDHGC4
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Sujet
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
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UniProt
- Q9Y5F7
Antigène
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