MCM8 anticorps (AA 598-840)

N° du produit ABIN7875936

L’anticorps anti-MCM8 Polyclonal Lapin est utilisé pour la détection de MCM8 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour MCM8 anticorps (AA 598-840) (ABIN7875936)

Antigène: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MCM8 anticorps

Épitope: AA 598-840

Fonction: MCM8 Antibody

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids N598-M840) was used as the immunogen for the MCM8 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MCM8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MCM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MCM8

Antigène: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Autre désignation: MCM8

Sujet: DNA replication licensing factor MCM8 is a protein that in humans is encoded by the MCM8 gene. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. And this protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

UniProt: Q9UJA3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA