Recombinant Villin 1 anticorps (AA 600-700)

N° du produit ABIN7876017

L’anticorps anti-Villin 1 Monoclonal Lapin est utilisé pour la détection de Villin 1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant Villin 1 anticorps (AA 600-700) (ABIN7876017)

Antigène: Villin 1 (VIL1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Villin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: VIL1-7378R

Détail du produit anti-Villin 1 anticorps

Épitope: AA 600-700

Fonction: Villin Antibody / VIL1

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 600-700) from the human protein was used as the immunogen for the Villin antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Villin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Villin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Villin 1

Antigène: Villin 1 (VIL1)

Autre désignation: Villin

Sujet: Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization