Recombinant L1CAM anticorps (AA 600-900)

N° du produit ABIN7876057

Cet anticorps anti-L1CAM Monoclonal Lapin (Clone L1CAM-13053R) (ABIN7876057) détecte spécifiquement L1CAM dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant L1CAM anticorps (AA 600-900) (ABIN7876057)

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: L1CAM-13053R

Détail du produit anti-L1CAM anticorps

Épitope: AA 600-900

Fonction: Neural cell adhesion molecule L1 Antibody / NCAM-L1

Purification: Protein A affinity

Immunogène: A portion of amino acids 600-900 from human L1CAM protein was used as the immunogen for the Neural cell adhesion molecule L1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Neural cell adhesion molecule L1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Neural cell adhesion molecule L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: Neural cell adhesion molecule L1

Sujet: L1 (L1 cell adhesion molecule) also known as CAML1, CD171, and HSAS is an adhesion molecule which plays an important role in the nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.

UniProt: P32004

Pathways: Synaptic Membrane