LARS anticorps (AA 628-855)
Aperçu rapide pour LARS anticorps (AA 628-855) (ABIN7876202)
Antigène
Voir toutes LARS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 628-855
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Fonction
- Leucyl tRNA synthetase Antibody / LARS
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Purification
- Antigen affinity purified
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Immunogène
- Amino acids Q628-Q855 from the human protein were used as the immunogen for the Leucyl tRNA synthetase antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Leucyl tRNA synthetase antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Leucyl tRNA synthetase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LARS (Leucyl-tRNA Synthetase (LARS))
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Autre désignation
- Leucyl tRNA synthetase
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Sujet
- Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene is mapped to 5q32. It encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed.
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UniProt
- Q9P2J5
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Pathways
- EGFR Signaling Pathway
Antigène
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