SEZ6L anticorps (AA 662-953)

N° du produit ABIN7876361

Cet anticorps Lapin Polyclonal détecte spécifiquement SEZ6L dans WB, ELISA, FACS et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SEZ6L anticorps (AA 662-953) (ABIN7876361)

Antigène: SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEZ6L est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-SEZ6L anticorps

Épitope: AA 662-953

Fonction: SEZ6L Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids E662-E953) was used as the immunogen for the SEZ6L antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SEZ6L antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SEZ6L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SEZ6L

Antigène: SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))

Autre désignation: SEZ6L

Sujet: Seizure 6-like protein is a protein that in humans is encoded by the SEZ6L gene. SEZ6L (Seizure 6-Like protein, also BSRP-B in rodent) is a 200 kDa member of the SEZ6 family of proteins. It is expressed in the plasma membrane and ER of CNS neurons and lung bronchiolar epithelium, and likely regulates PKC alpha activation. Mature human SEZ6L is a 996 amino acid (aa) type I transmembrane protein. It contains a 930 aa extracellular domain (ECD) (aa 29-958) plus a 45 aa cytoplasmic tail. The ECD shows three CUB domains and five short consensus repeats (SCRs). There are multiple isoforms possible for SEZ6L. One shows a deletion of aa 933-943, and a second shows the same deletion coupled to a Thr substitution for aa 803-867. A third isoform contains a Leu substitution for aa 867-943. An alternative start site is reported at Met228. This start site may occur individually, or be accompanied by a deletion of aa 932-944, the same deletion of aa 932-944 coupled to a Thr substitution for aa 803-867, or a duel deletion of aa 869-945 and 1016-1024. Over aa 29-958, human BSRP-B is 80 % aa identical to mouse BSRP-B.

UniProt: Q9BYH1