UVRAG anticorps (AA 666-699)

N° du produit ABIN7876363

Cet anticorps anti-UVRAG Polyclonal Lapin (ABIN7876363) détecte spécifiquement UVRAG dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour UVRAG anticorps (AA 666-699) (ABIN7876363)

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UVRAG est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-UVRAG anticorps

Épitope: AA 666-699

Fonction: UVRAG Antibody

Purification: Purified

Immunogène: A portion of amino acids 666-699 from the human protein was used as the immunogen for the UVRAG antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the UVRAG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the UVRAG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur UVRAG

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Autre désignation: UVRAG

Sujet: UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

UniProt: Q9P2Y5