Cet anticorps anti-CDK14 Polyclonal Lapin (ABIN7876387) détecte spécifiquement CDK14 dans WB, FACS et IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
The stated application concentrations are suggested starting points. Titration of the CDK14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the CDK14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
CDK14
(Cyclin-Dependent Kinase 14 (CDK14))
Autre désignation
CDK14
Sujet
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. [UniProt]