PRELP anticorps (AA 69-353)

N° du produit ABIN7876441

Cet anticorps anti-PRELP Polyclonal Lapin (ABIN7876441) détecte spécifiquement PRELP dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PRELP anticorps (AA 69-353) (ABIN7876441)

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRELP est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PRELP anticorps

Épitope: AA 69-353

Fonction: Prolargin Antibody / PRELP

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids I69-R353) was used as the immunogen for the Prolargin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Prolargin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Prolargin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PRELP

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Autre désignation: Prolargin

Sujet: Prolargin is a protein that in humans is encoded by the PRELP gene. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

UniProt: P51888

Pathways: Glycosaminoglycan Metabolic Process