Titration of the DCAMKL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the DCAMKL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
DCLK1
(Doublecortin-Like Kinase 1 (DCLK1))
Autre désignation
DCAMKL1
Sujet
This gene encodes a member of the protein kinase superfamily and the doublecortin family called Doublecortin-like and CAM kinase-like 1 (DCAMKL1) or Doublecortin-like kinase 1 (DCLK1). The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity.