DR1 anticorps (AA 7-154)

N° du produit ABIN7876466

Cet anticorps Lapin Polyclonal détecte spécifiquement DR1 dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DR1 anticorps (AA 7-154) (ABIN7876466)

Antigène: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-DR1 anticorps

Épitope: AA 7-154

Fonction: DR1 Antibody / Down-regulator of transcription 1

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids N7-A154) was used as the immunogen for the DR1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DR1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the DR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur DR1

Antigène: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Autre désignation: DR1

Sujet: Protein Dr1 is a protein that in humans is encoded by the DR1 gene. This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

UniProt: Q01658