Ribonuclease H1 anticorps (AA 7-223)

N° du produit ABIN7876470

L’anticorps anti-Ribonuclease H1 Polyclonal Lapin est utilisé pour la détection de Ribonuclease H1 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour Ribonuclease H1 anticorps (AA 7-223) (ABIN7876470)

Antigène: Ribonuclease H1 (RNASEH1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ribonuclease H1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-Ribonuclease H1 anticorps

Épitope: AA 7-223

Fonction: Ribonuclease H1 Antibody / RNASEH1

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids L7-Q223) was used as the immunogen for the Ribonuclease H1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Ribonuclease H1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Ribonuclease H1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Ribonuclease H1

Antigène: Ribonuclease H1 (RNASEH1)

Autre désignation: Ribonuclease H1

Sujet: Ribonuclease H1 also known as RNase H1 is an enzyme that in humans is encoded by the RNASEH1 gene. This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17.

UniProt: O60930