CD276 anticorps (AA 7-3, AA 100-300)
Aperçu rapide pour CD276 anticorps (AA 7-3, AA 100-300) (ABIN7876485)
Antigène
Voir toutes CD276 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 7-3, AA 100-300
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Fonction
- B7-H3 Antibody / CD276
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Purification
- Protein A/G affinity
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Immunogène
- A portion of amino acids 100-300 from the human CD276 protein was used as the immunogen for the B7-H3 antibody.
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Isotype
- IgG2b, kappa
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anti-CD276 (CD276) (AA 47-219) antibody
CD276 Reactivité: Humain WB, IHC, FACS Hôte: Lapin Polyclonal unconjugated
anti-CD276 (CD276) (C-Term) antibodyCD276 Reactivité: Humain, Souris WB, IHC, FACS, IP, ICC, IF (p) Hôte: Lapin Monoclonal BLR025F unconjugated Recombinant Antibody
anti-CD276 (CD276) (AA 29-466) antibodyCD276 Reactivité: Humain ELISA, IHC, FACS, ICC Hôte: Souris Monoclonal 8C1C2 unconjugated
anti-CD276 (CD276) (AA 493-522), (C-Term) antibodyCD276 Reactivité: Humain WB, FACS, IHC (p), IF Hôte: Lapin Polyclonal RB31111 unconjugated
anti-CD276 (CD276) (AA 47-213) antibodyCD276 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-CD276 (CD276) (AA 29-465) antibodyCD276 Reactivité: Humain WB, IHC, FACS, IP, ICC Hôte: Lapin Monoclonal BLR026F unconjugated Recombinant Antibody
anti-CD276 (CD276) (AA 29-458) antibodyCD276 Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated
anti-CD276 (CD276) (AA 237-358) antibodyCD276 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 4E12 unconjugated
anti-CD276 (CD276) (AA 100-200) antibodyCD276 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-CD276 (CD276) antibodyKD Validated CD276 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB5035 unconjugated Recombinant Antibody
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Indications d'application
- Optimal dilution of the B7-H3 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the B7-H3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD276
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Autre désignation
- B7-H3
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Sujet
- T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory molecules. One such molecule, B7-H3 (B7-homolog 3, also designated B7RP-2 and CD276) belongs to the B7 immunoglobulin superfamily. Soluble B7-H3 binds a putative receptor on activated T-cells that is distinct from CD28, CTLA-4, ICOS and PD-1. Widely expressed on nonlymphoid tissues, B7-H3 costimulates proliferation of both CD4+ and CD8+ T cells. The ability of B7-H3 to stimulate Th1 and cytotoxic-T cell responses suggest that it may have antitumor activity. B7-H3 interactions may play a role in regulating cell-mediated immune responses against cancer, implicating B7-H3 as a potential therapeutic tool.
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UniProt
- Q5ZPR3
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Pathways
- Cancer Immune Checkpoints
Antigène
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