Recombinant RRM1 anticorps (AA 700-800)

N° du produit ABIN7876550

Cet anticorps Lapin Monoclonal détecte spécifiquement RRM1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant RRM1 anticorps (AA 700-800) (ABIN7876550)

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RRM1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RRM1-4372R

Détail du produit anti-RRM1 anticorps

Épitope: AA 700-800

Fonction: RRM1 Antibody / Ribonucleotide Reductase M1

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 700-800 of human RRM1 was used as the immunogen for the RRM1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RRM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RRM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur RRM1

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Autre désignation: RRM1

Sujet: Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity