Recombinant CD7 anticorps (AA 72-175)

N° du produit ABIN7876631

Cet anticorps Lapin Monoclonal détecte spécifiquement CD7 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD7 anticorps (AA 72-175) (ABIN7876631)

Antigène: CD7

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CD7-8496R

Détail du produit anti-CD7 anticorps

Épitope: AA 72-175

Fonction: Recombinant CD7 Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 72-175) from the human protein was used as the immunogen for the recombinant CD7 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CD7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant CD7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD7

Antigène: CD7

Autre désignation: CD7

Sujet: Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

UniProt: P09564

Pathways: Cell-Cell Junction Organization