SAP130 anticorps (AA 728-1181)

N° du produit ABIN7876645

Cet anticorps anti-SAP130 Polyclonal Lapin (ABIN7876645) détecte spécifiquement SAP130 dans WB, ELISA, IHC (p), IF et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SAP130 anticorps (AA 728-1181) (ABIN7876645)

Antigène: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAP130 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-SAP130 anticorps

Épitope: AA 728-1181

Fonction: SAP130 Antibody / SF3B3

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids R728-Q1181) was used as the immunogen for the SAP130 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SAP130 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SAP130 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SAP130

Antigène: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Autre désignation: SAP130

Sujet: Splicing factor 3B subunit 3 is a protein that in humans is encoded by the SF3B3 gene. This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

UniProt: Q15393