MAEL anticorps (AA 73-347)
Aperçu rapide pour MAEL anticorps (AA 73-347) (ABIN7876680)
Antigène
Voir toutes MAEL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 73-347
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Fonction
- MAEL Antibody / Maelstrom homolog
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (E73-Q347) was used as the immunogen for the MAEL antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the MAEL antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the MAEL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))
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Autre désignation
- MAEL
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Sujet
- The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
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UniProt
- Q96JY0
Antigène
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