Recombinant CD207 anticorps (AA 74-213)
Aperçu rapide pour Recombinant CD207 anticorps (AA 74-213) (ABIN7876704)
Antigène
Voir toutes CD207 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 74-213
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Fonction
- Recombinant Langerin Antibody / CD207 (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- A portion of amino acids 74-213 was used as the immunogen for the recombinant Langerin antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the recombinant Langerin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the recombinant Langerin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD207 (CD207 Molecule, Langerin (CD207))
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Autre désignation
- Langerin
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Sujet
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
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UniProt
- Q9UJ71
Antigène
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