CD207 anticorps (AA 74-213)

N° du produit ABIN7876709

Cet anticorps Souris Monoclonal détecte spécifiquement CD207 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD207 anticorps (AA 74-213) (ABIN7876709)

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: LGRN-1821

Détail du produit anti-CD207 anticorps

Épitope: AA 74-213

Fonction: Langerin Antibody / CD207

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 74-213) was used as the immunogen for the Langerin antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Langerin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Langerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: Langerin

Sujet: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

UniProt: Q9UJ71