Cet anticorps anti-SYCP3 Polyclonal Lapin (ABIN7876729) détecte spécifiquement SYCP3 dans WB, ELISA, IF, IHC (p) et FACS.
L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.
Optimal dilution of the Synaptonemal Complex Protein 3 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the Synaptonemal Complex Protein 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
SYCP3
(Synaptonemal Complex Protein 3 (SYCP3))
Autre désignation
Synaptonemal Complex Protein 3
Sujet
SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.