Neurexin 1 anticorps (AA 77-110)

N° du produit ABIN7876757

Cet anticorps Lapin Polyclonal détecte spécifiquement Neurexin 1 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Neurexin 1 anticorps (AA 77-110) (ABIN7876757)

Antigène: Neurexin 1 (NRXN1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurexin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Neurexin 1 anticorps

Épitope: AA 77-110

Fonction: NRXN1 Antibody / Neurexin 1 beta

Purification: Antigen affinity

Immunogène: A portion of amino acids 77-110 from the human protein was used as the immunogen for this NRXN1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the NRXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4oC for up to one month. For long term, aliquot the NRXN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Neurexin 1

Antigène: Neurexin 1 (NRXN1)

Autre désignation: NRXN1

Sujet: Neurexin 1 is primarily known for its role in the formation and maintenance of synapses, the connections between neurons that allow for communication in the brain. It acts as a cell adhesion molecule, helping to guide the development of synapses and ensuring proper signaling between neurons. Studies have shown that mutations in the NRXN1 gene can lead to disruptions in synaptic function, ultimately impacting brain development and function. These mutations have been associated with a variety of neurological disorders, including autism spectrum disorder, schizophrenia, and intellectual disabilities.

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development