SNX15 anticorps (AA 8-327)

N° du produit ABIN7876821

L’anticorps anti-SNX15 Polyclonal Lapin est utilisé pour la détection de SNX15 dans des échantillons de Humain. Il a été validé pour ELISA et WB.

Aperçu rapide pour SNX15 anticorps (AA 8-327) (ABIN7876821)

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX15 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-SNX15 anticorps

Épitope: AA 8-327

Fonction: Sorting nexin 15 Antibody / SNX15

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids D8-K327) was used as the immunogen for the Sorting nexin 15 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Sorting nexin 15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Sorting nexin 15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SNX15

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Autre désignation: Sorting nexin 15

Sujet: Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

UniProt: Q9NRS6