FLCN anticorps (AA 8-551)

N° du produit ABIN7876838

Cet anticorps Lapin Polyclonal détecte spécifiquement FLCN dans WB, ELISA, IF, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FLCN anticorps (AA 8-551) (ABIN7876838)

Antigène: FLCN (Folliculin (FLCN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLCN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FLCN anticorps

Épitope: AA 8-551

Fonction: Folliculin Antibody / FLCN

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids C8-K551) was used as the immunogen for the Folliculin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Folliculin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Folliculin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur FLCN

Antigène: FLCN (Folliculin (FLCN))

Autre désignation: Folliculin

Classe de substances: Amino Acid

Sujet: Folliculin also known as FLCN, Birt-Hogg-Dube syndrome protein or FLCN_HUMAN is a protein that in humans is associated with Birt-Hogg-Dube syndrome and hereditary spontaneous pneumothorax. It is encoded by the Folliculin (FLCN) gene (alias BHD, FLCL) that acts as a tumor suppressor gene. It is mapped to 17p11.2. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization