EIF3C anticorps (AA 81-637)
Aperçu rapide pour EIF3C anticorps (AA 81-637) (ABIN7876897)
Antigène
Voir toutes EIF3C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 81-637
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Fonction
- EIF3C Antibody / Eukaryotic translation initiation factor 3 subunit C
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Purification
- Antigen affinity purified
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Immunogène
- E. coli-derived recombinant human protein (amino acids E81-Q637) was used as the immunogen for the EIF3C antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the EIF3C antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the EIF3C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
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Autre désignation
- EIF3C
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Sujet
- Eukaryotic translation initiation factor 3 subunit C (eIF3c) is a protein that in humans is encoded by the EIF3C gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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UniProt
- Q99613
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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