VWF anticorps (AA 845-949)

N° du produit ABIN7876965

L’anticorps anti-VWF Monoclonal Souris est utilisé pour la détection de VWF dans des échantillons de Humain, Rat et Souris. Il a été validé pour IHC (p).

Aperçu rapide pour VWF anticorps (AA 845-949) (ABIN7876965)

Antigène: VWF (Von Willebrand Factor (VWF))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VWF est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: VWF-4105

Détail du produit anti-VWF anticorps

Épitope: AA 845-949

Fonction: von Willebrand Factor Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant human vWF fragment protein sequence (within amino acids 845-949) was used as the immunogen for the von Willebrand Factor antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the von Willebrand Factor antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the von Willebrand Factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur VWF

Antigène: VWF (Von Willebrand Factor (VWF))

Autre désignation: von Willebrand Factor

Sujet: Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

UniProt: P04275