MVP anticorps (AA 863-893)
Aperçu rapide pour MVP anticorps (AA 863-893) (ABIN7877005)
Antigène
Voir toutes MVP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 863-893
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Fonction
- Major Vault Protein Antibody / MVP
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Purification
- Purified
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Immunogène
- A portion of amino acids 863-893 from the human protein was used as the immunogen for the Major Vault Protein antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the Major Vault Protein antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Major Vault Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MVP (Major Vault Protein (MVP))
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Autre désignation
- Major Vault Protein
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Sujet
- MVP, the major vault protein, is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance.
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UniProt
- Q14764
Antigène
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