PFN2 anticorps (AA 87-139)

N° du produit ABIN7877014

Cet anticorps anti-PFN2 Polyclonal Lapin (ABIN7877014) détecte spécifiquement PFN2 dans WB. L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour PFN2 anticorps (AA 87-139) (ABIN7877014)

Antigène: PFN2 (Profilin 2 (PFN2))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PFN2 anticorps

Épitope: AA 87-139

Fonction: Zebrafish Pfn2 Antibody / Profilin 2 / Isoforms a & b

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Pfn2a/b recombinant protein (amino acids I87-F139) was used as the immunogen for the Zebrafish Pfn2 antibody. This antibody will detect the a and b isoforms.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Pfn2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Pfn2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PFN2

Antigène: PFN2 (Profilin 2 (PFN2))

Autre désignation: Pfn2

Sujet: Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

UniProt: Q6AZA1

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis