BSCL2 anticorps (AA 87-231)

N° du produit ABIN7877016

L’anticorps anti-BSCL2 Polyclonal Lapin est utilisé pour la détection de BSCL2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour BSCL2 anticorps (AA 87-231) (ABIN7877016)

Antigène: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BSCL2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BSCL2 anticorps

Épitope: AA 87-231

Fonction: Seipin Antibody / BSCL2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids A87-P231) was used as the immunogen for the Seipin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Seipin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Seipin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur BSCL2

Antigène: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Autre désignation: Seipin

Sujet: Seipin is a protein that in humans is encoded by the BSCL2 gene. This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).

UniProt: Q96G97