PC anticorps (AA 88-1165)
Aperçu rapide pour PC anticorps (AA 88-1165) (ABIN7877025)
Antigène
Voir toutes PC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 88-1165
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Fonction
- Pyruvate Carboxylase Antibody / PC
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids R88-D1165) was used as the immunogen for the Pyruvate Carboxylase antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Pyruvate Carboxylase antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Pyruvate Carboxylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PC (Pyruvate Carboxylase (PC))
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Autre désignation
- Pyruvate Carboxylase
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Sujet
- This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
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UniProt
- P11498
Antigène
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