SOGA2 anticorps (AA 884-1522)

N° du produit ABIN7877038

Cet anticorps anti-SOGA2 Polyclonal Lapin (ABIN7877038) détecte spécifiquement SOGA2 dans WB, ELISA, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SOGA2 anticorps (AA 884-1522) (ABIN7877038)

Antigène: SOGA2 (SOGA Family Member 2 (SOGA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOGA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-SOGA2 anticorps

Épitope: AA 884-1522

Fonction: MTCL1 Antibody / Microtubule cross-linking factor 1 / KIAA0802

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (K884-D1522) was used as the immunogen for the MTCL1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MTCL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MTCL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SOGA2

Antigène: SOGA2 (SOGA Family Member 2 (SOGA2))

Autre désignation: MTCL1

Sujet: MTCL1 (microtubule cross-linking factor 1), also known as CCDC165 (Coiledcoil domain-containing protein 165), SOGA2 or MTCL1, is a 1,905 amino acid protein that localizes to the cell membrane, cytoplasm and cytoskeleton. MTCL1 is a microtubule-associated factor that plays a role in regulating polarization and microtubule dynamics as well as the development and maintenance of non-centrosomal microtubule bundles. MTCL1 is encoded by a gene that maps to chromosome 18 and is expressed as four isoforms due to alternative splicing events. Chromosome 18 encodes over 300 genes and contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF? modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.

UniProt: Q9Y4B5