Bestrophin 1 anticorps (AA 9-551)

N° du produit ABIN7877093

Cet anticorps Lapin Polyclonal détecte spécifiquement Bestrophin 1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour Bestrophin 1 anticorps (AA 9-551) (ABIN7877093)

Antigène: Bestrophin 1 (BEST1)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Bestrophin 1 anticorps

Épitope: AA 9-551

Fonction: Best1 Antibody / Bestrophin 1

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived mouse recombinant protein (amino acids V9-E551) was used as the immunogen for the Best1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Best1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Best1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: Best1

Sujet: Bestrophin-1 (Best1) is a protein that in humans is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

UniProt: O88870