Cet anticorps Lapin Polyclonal détecte spécifiquement GRIN1/NMDAR1 dans IHC (p). Il présente une réactivité avec des échantillons de Poisson zèbre (Danio rerio).
A synthetic peptide corresponding to a sequence at the C-terminus of zebrafish Grin1a/b was used as the immunogen for the Zebrafish Grin1 antibody. This antibody will detect isoforms a & b.
Optimal dilution of the Zebrafish Grin1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the Zebrafish Grin1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Glutamate [NMDA] receptor subunit zeta-1 is a protein that in humans is encoded by the GRIN1 gene. The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.