Trefoil Factor 2 anticorps (C-Term)
Aperçu rapide pour Trefoil Factor 2 anticorps (C-Term) (ABIN7877489)
Antigène
Voir toutes Trefoil Factor 2 (TFF2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Fonction
- TFF2 Antibody / Trefoil factor 2
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Purification
- PEG precipitation
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Immunogène
- A synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2 protein was used as the immunogen for this TFF2 antibody.
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Isotype
- IgM, kappa
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Indications d'application
- Optimal dilution of the TFF2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the TFF2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Trefoil Factor 2 (TFF2)
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Autre désignation
- TFF2
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Sujet
- Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.
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UniProt
- Q03403
Antigène
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