Recombinant VLDLR anticorps (C-Term)

N° du produit ABIN7877495

Cet anticorps Souris Monoclonal détecte spécifiquement VLDLR dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant VLDLR anticorps (C-Term) (ABIN7877495)

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VLDLR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RVLDLR-1337

Détail du produit anti-VLDLR anticorps

Épitope: C-Term

Fonction: VLDLR Antibody / VLDL Receptor

Purification: Protein A/G affinity

Immunogène: A recombinant human protein fragment from the C-terminal region was used as the immunogen for the VLDLR antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the VLDLR antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the VLDLR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur VLDLR

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Autre désignation: VLDLR

Sujet: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin