CTBP2 anticorps (C-Term, full length)

N° du produit ABIN7877506

Cet anticorps anti-CTBP2 Monoclonal Souris (Clone PCRP-CTBP2-2D11) (ABIN7877506) détecte spécifiquement CTBP2 dans IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CTBP2 anticorps (C-Term, full length) (ABIN7877506)

Antigène: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTBP2 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-CTBP2-2D11

Détail du produit anti-CTBP2 anticorps

Épitope: C-Term, full length

Fonction: C-terminal-binding protein 2 Antibody / CTBP2

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human CTBP2/C-terminal-binding protein 2 protein was used as the immunogen for the C-terminal-binding protein 2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the C-terminal-binding protein 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the C-terminal-binding protein 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CTBP2

Antigène: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Autre désignation: C-terminal-binding protein 2

Sujet: The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.

UniProt: P56545