IL-10RA anticorps (Extracellular)
Aperçu rapide pour IL-10RA anticorps (Extracellular) (ABIN7877550)
Antigène
Voir toutes IL-10RA (IL10RA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular
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Fonction
- IL-10RA Antibody / IL-10R1
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Purification
- Protein G affinity chromatography
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Immunogène
- Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the IL-10RA antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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Autre désignation
- IL-10RA
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Sujet
- This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
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UniProt
- Q61727
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Pathways
- Growth Factor Binding
Antigène
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