BCL6 anticorps (full length)
Aperçu rapide pour BCL6 anticorps (full length) (ABIN7877696)
Antigène
Voir toutes BCL6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Bcl6 Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human protein was used as the immunogen for the Bcl6 antibody.
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal dilution of the Bcl6 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Bcl6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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Autre désignation
- Bcl6
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Sujet
- Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
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UniProt
- P41182
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Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Antigène
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