CD7 anticorps (full length)

N° du produit ABIN7877947

Cet anticorps anti-CD7 Monoclonal Souris (Clone CD7-3737) (ABIN7877947) détecte spécifiquement CD7 dans ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD7 anticorps (full length) (ABIN7877947)

Antigène: CD7

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD7 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CD7-3737

Détail du produit anti-CD7 anticorps

Épitope: full length

Fonction: CD7 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human full-length CD7 protein was used as the immunogen for this CD7 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the CD7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CD7

Antigène: CD7

Autre désignation: CD7

Sujet: Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

UniProt: P09564

Pathways: Cell-Cell Junction Organization