CHID1 anticorps (full length)

N° du produit ABIN7877977

Cet anticorps anti-CHID1 Monoclonal Souris (Clone CHID1-6368) (ABIN7877977) détecte spécifiquement CHID1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CHID1 anticorps (full length) (ABIN7877977)

Antigène: CHID1 (Chitinase Domain Containing 1 (CHID1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CHID1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CHID1-6368

Détail du produit anti-CHID1 anticorps

Épitope: full length

Fonction: SI-CLP Antibody / CHID1

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human SI-CLP protein was used as the immunogen for the CHID1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the SI-CLP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SI-CLP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CHID1

Antigène: CHID1 (Chitinase Domain Containing 1 (CHID1))

Autre désignation: SI-CLP

Sujet: SI-CLP (stabilin-1 interacting chitinase-like), also known as CHID1 (chitinase domain-containing protein 1), is a 393 amino acid secreted protein that belongs to the glycosyl hydrolase 18 family. SI-CLP interacts with STAB1 and localizes to lysosome in cells of monocytic, T, B and epithelial origin. SI-CLP is a saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). The SI-CLP protein is up-regulated by IL4/interleukin-4 and dexamethasone in the macrophages, and is also up-regulated by glucocorticoid. Existing as three alternatively spliced isoforms, the SI-CLP gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A. thaliana and rice, and maps to human chromosome 11p15.5.

UniProt: Q9BWS9