CKM anticorps (full length)

N° du produit ABIN7878038

Cet anticorps Souris Monoclonal détecte spécifiquement CKM dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CKM anticorps (full length) (ABIN7878038)

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CKM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CKMM-3341

Détail du produit anti-CKM anticorps

Épitope: full length

Fonction: Creatine Kinase M Antibody / CKM

Purification: Protein G affinity chromatography

Immunogène: Recombinant full-length CKM protein was used as the immunogen for the Creatine Kinase M antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Creatine Kinase M antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Creatine Kinase M antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CKM

Antigène: CKM (Creatine Kinase, Muscle (CKM))

Autre désignation: Creatine Kinase M

Sujet: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

UniProt: P06732