DAXX anticorps (full length)

N° du produit ABIN7878116

Cet anticorps Souris Monoclonal détecte spécifiquement DAXX dans IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DAXX anticorps (full length) (ABIN7878116)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DAXX est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-DAXX-6A8

Détail du produit anti-DAXX anticorps

Épitope: full length

Fonction: Daxx Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human DAXX protein was used as the immunogen for the Daxx antibody.

Isotype: IgG2c

Information d'application

Indications d'application: Optimal dilution of the Daxx antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Daxx antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur DAXX

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Autre désignation: Daxx

Sujet: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway