DAXX anticorps (full length)

N° du produit ABIN7878117

L’anticorps anti-DAXX Monoclonal Souris est utilisé pour la détection de DAXX dans des échantillons de Humain. Il a été validé pour IF et FACS.

Aperçu rapide pour DAXX anticorps (full length) (ABIN7878117)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DAXX est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-DAXX-6A8

Détail du produit anti-DAXX anticorps

Épitope: full length

Fonction: Daxx Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human DAXX protein was used as the immunogen for the Daxx antibody.

Isotype: IgG2c

Information d'application

Indications d'application: Optimal dilution of the Daxx antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Daxx antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur DAXX

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Autre désignation: Daxx

Sujet: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway