DMRT2 anticorps (full length)

N° du produit ABIN7878145

Cet anticorps anti-DMRT2 Monoclonal Souris (Clone PCRP-DMRT2-1B11) (ABIN7878145) détecte spécifiquement DMRT2 dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DMRT2 anticorps (full length) (ABIN7878145)

Antigène: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DMRT2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: PCRP-DMRT2-1B11

Détail du produit anti-DMRT2 anticorps

Épitope: full length

Fonction: DMRT2 Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human DMRT2 protein was used as the immunogen for the DMRT2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the DMRT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DMRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur DMRT2

Antigène: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Autre désignation: DMRT2

Sujet: The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

UniProt: Q9Y5R5