FSHB anticorps (full length)
Aperçu rapide pour FSHB anticorps (full length) (ABIN7878242)
Antigène
Voir toutes FSHB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- full length
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Fonction
- FSH-beta Antibody
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Purification
- Protein G affinity chromatography
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Immunogène
- Full length purified hFSH was used as the immunogen for the FSH-beta antibody.
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Isotype
- IgG1, kappa
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Indications d'application
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Optimal dilution of the FSH-beta antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the FSH-beta antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))
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Autre désignation
- FSH-beta
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Sujet
- This mAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
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UniProt
- P01225
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Pathways
- Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
Antigène
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